Depo-medrone V Suspension is recommended for intramuscular and intrasynovial injection in horses and dogs, and intramuscular injection in cats. Depo-medrone V Suspension is available in two concentrations, 20 mg per mL and 40 mg per mL.
INDICATIONS AND USAGE
As with other adrenal steroids, Depo-medrone has been found useful in alleviating the pain and lameness associated with acute localized arthritic conditions and generalized arthritic conditions. It has been used successfully to treat rheumatoid arthritis, traumatic arthritis, osteoarthritis, periostitis, tendinitis, synovitis, tenosynovitis, bursitis, and myositis of horses; traumatic arthritis, osteoarthritis, and generalized arthritic conditions of dogs. Remission of musculoskeletal conditions may be permanent, or symptoms may recur, depending on the cause and extent of structural degeneration.
Depo-medrone V Suspension is especially beneficial in relieving pruritus and inflammation of allergic dermatitis, acute moist dermatitis, dry eczema, urticaria, bronchial asthma, pollen sensitivities and otitis externa in dogs; allergic dermatitis and moist and dry eczema in cats. Onset of relief may begin within a few hours to a few days following injection and may persist for a few days to six weeks. Symptoms may be expected to recur if the cause of the allergic reaction is still present, in which case retreatment may be indicated. In treating acute hypersensitivity reactions, such as anaphylactic shock, intravenous SOLU-DELTA-CORTEF Sterile Powder containing prednisolone sodium succinate, as well as other appropriate treatments, should be used.
Depo-medrone V Suspension is used in horses to treat (or as part of a therapeutic regime for), musculo-skeletal conditions. It can be given intra-muscularly (not intra-venously) for it’s anti-inflammatory effects or intra-articularly (into a joint). After intra-articular injection, improvement of clinical signs should be seen within 24-48hours; this lasts for an average of 3-4 weeks, but is variable. Working animals should be rested after treatment, to allow the clinical condition to resolve. Long term repeated injections are not recommended.
In cats & dogs, it can also be given intra-muscularly or intra-articularly depending on the condition. It is used in the treatment of allergic or inflammatory conditions, including skin conditions; musculo-skeletal conditions; ocular/otic (ear/eye) inflammatory conditions & autoimmune disorders.
The average initial dose of Depo-medrone V Suspension for a large synovial space is 120 mg (3 ml). Smaller spaces will require a correspondingly lesser dose. The intratendinous dose ranges from 80–400 mg (2–10 ml) depending on the size of the tendon.
The average initial dosage for a large synovial space is 20 mg (0.5 ml). Smaller spaces will require a correspondingly lesser dosage.