Ichon is a preservative-free sterile solution used only by veterinarians after surgery to help prevent adhesions and strengthen scars in animals. Ichon is used by veterinarians after surgery to prevent adhesions and strengthen scars.
Normally, joint cartilages have proteoglycan complexes, which are proteins with side chains made of glycosaminoglycans such as keratan sulfate and chondroitin sulfate attached to strands of hyaluronic acid. The glycosaminoglycan side chains are polyanionic, which causes adjacent side chains to push each other away and create a “bottle brush”, where hyaluronic acid is the stem and the side chains are the bristles. When pressure is exerted on the joint, fluids move between the chondrocytes and synovial fluid, exchanging nutrients. In degenerative joint disease, the proteoglycan complexes start disappearing, and the hyaluronate becomes poorer in quality and scarcer.
This lowers the viscosity of the synovial fluid (which increases friction) and causes white blood cells and enzymes to enter and effect cartilage degradation and inflammation. Steroids that are released as a result kill the chondrocytes. The remaining chondrocytes have trouble exchanging nutrients with the synovial fluid, which would allow them to repair some damages. Ichon also stimulates the synthesis of glycosaminoglycans, hyaluronic acid, and collagen, which increase synovial viscosity. It cannot, however, completely reverse the disappearance of cartilage, nor can it reverse bone loss caused by arthritis.
- Intraperitoneal prophylactic agent for prevention of adhesions
- Post-surgical lavage to prevent adhesions in gynaecological procedures
- Ichon Strengthen post surgical scar
- Sterile Polysulfated Glycosaminoglycan
- 500 mg of sterile PSGAG per 5ml vial (100mg/ml)
- Ichon is Derived from Bovine Trachea
- Ichon is Tested by independent certified lab to be a Polysulfated
- Uses Sterile Lavage
- Marketed as a Medical Device
Directions for Use
- Install this medical device as the final lavage prior to surgical closure of the abdominal incision
- Install at a rate of 0.013 grams / kg in a 0.9% sterile NaCl solution
- Volume to be determined by veterinary surgeon
- Discard any unused portion of vial contents