Regumate Equine is used to control oestrus (“heat”) in mares. It is supplied as a liquid to be given directly into the mouth, or added to a small amount of food. It can be given daily to a mare early in her season and usually within 3 days it will stop that oestrus. Regumate can continue to be given once daily afterwards to prevent the return to oestrus. When daily dosing stops, 95% of mares will show signs of returning to oestrus within 5 days.
Regumate is usually used to prevent the hormone-dependant behavioural changes associated with oestrus, or to control the timing of ovulation so that the timing of mating and birth can be organised.
Regumate Equine is a clear, light yellow oily solution. Each ml of Regumate Equine contains Altrenogest 2.20 mg as active sustance and Butylhydroxyanisole (E3210) 0.07mg, Butylhydroxytoluene (E321) 0.07mg, Sorbic acid (E200) 1.50mg and Benzyl alcohol 10.00mg as excipients.
In mares with significant follicular activity during the transitional period between seasonal anoestrus and the breeding season (follicles of at least 20-25mm present at the beginning of treatment):
– Suppression/prevention of oestrus (usually after 1 to 3 days of treatment) during the prolonged oestrus periods occurring during this period.
– Control of the time of initiation of oestrus (approximately 90% of mares show signs of oestrus within 5 days following the end of treatment) and synchronization of ovulation (60% of mares ovulate between days 11 and 14 following the end of treatment).
Contra-indications Regumate Equine
Do not use in mares where uterine infection has been diagnosed.
Do not use in males.
Do not use in mares which produces milk for human consumption.
Adverse reactions, such as uterine infection, are extremely rare.
Dosage and administration:
The recommended dosage is 0.044 mg altrenogest per kg bodyweight per day, for 10 consecutive days. Carefully withdraw the volume of product corresponding to the mare bodyweight (1 ml per 50 kg bodyweight) and administer this volume via oral route.
Remove the original cap and in its place screw on the luer lock cap. Keeping the bottle upright, screw the syringe onto the luer lock cap orifice, turn the bottle upside down, and carefully withdraw the solution from the bottle using the syringe. Turn the bottle right way up before detaching the syringe. Securely replace the small cap on the luer lock cap.